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Product News2015/07/22
Exploring the effects of DPP-4 inhibitor (sitagliptin) or Biguanide (metformin) for improving blood glucose controls in T2 diabetes Japanese patients inadequately controlled with insulin therapy.
We would like to introduce an article that evaluates whether DPP-4 inhibitor (sitagliptin) or Biguanide (metformin) improves blood glucose control via different effects on the secretion of insulin and glucagon, as well as incretin level in T2 diabetes Japanese patients who poorly controlled with insulin monotherapy.
 
The article suggests that the effect of glucagon suppression of DPP-4 inhibitor (sitagliptin) could be one of the factor of improving blood glucose control in patients poorly controlled with insulin monotherapy. Please click the link below and read the original article for further details.

Addition of sitagliptin or metformin to insulin monotherapy improves blood glucose control via different effects on insulin and glucagon secretion in hyperglycemic Japanese patients with type 2 diabetes. Otsuka Y et al. Endocr J. 2015;62(2):133-43 PMID 25328079

The following our incretin related assay kits are used in the article.
#27784 GLP-1, Active form Assay Kit - IBL
#27201 Human GIP, Active form Assay Kit - IBL
#27203 Human GIP, Total Assay Kit - IBL

Incretin related product lineup

We are going to exhibit at EASD 2015 in Stockholm. 

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