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#10363 Anti-Mouse BEC12 (LA5) Rat IgG MoAb

  • Frozen section, superficial part of mouse tongue, x400
  • Frozen section, deep part of mouse tongue, x400
Intended Use：
Research reagents
Application：
IHC
Package Size1：
100 μg
Package Size2：
10 μg
Note on Application Abbreviations
IHC:Immunohistochemistry

※ The product indicated as "Research reagents" in the column Intended Use cannot be used
　 for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
　 enclosed in the product purchased before use.

Product Overview

Product Overview

Product Code 10363
Product Name Anti-Mouse BEC12 (LA5) Rat IgG MoAb
Intended Use Research reagents
Application IHC
Species Mouse
Immunizing antigen Mouse lymphangioma
Source Rat-Mouse hybridoma
Clone Name LA5
Subclass IgG2a, κ
Purification Method Affinity purified with antigen
Specificity Reacts to about 12 kDa protein antigen on the blood vascular endothelialmembrane of mouse.
Not cross-react with endothelial cells of lymph vessels or large-medium-sizedarteries and veins, but cross-reacts with some lymphatic cells.
Not cross-react with human, rat or guinea pig.
Package Form Lyophilized product from 1 % BSA in PBS containing 0.05 % NaN3
Storage Condition 2 - 8℃
Poisonous and Deleterious Substances Applicable
Cartagena Not Applicable
Package Size 1 100 μg
Package Size 2 10 μg
Remarks1 The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission.

Product Description

Product Description

Recent years, specific antigens of vascular endothelium have been found one after another, and they contribute to progress of vascular biology. This antibody, being unlike any other prior antibodies, reacts especially with arterial microcirculating system including small arteries and blood capillaries, and also reacts with some small venous endothelial cells. This is an unprecedented type (site-specific) of anti vascular endothelium antibody, generated with an adjuvant-induced benignant lymphangioma (intra-abdominal tumor) by “rapid differential immunization technique” (a more efficient immunization method for antigens which are weak in antigenicity.) It doesn’t react with endothelial cells of lymph vessels but reacts with some blood cells. Photos are kindly provided by Dr. Taichi Ezaki, Department of Anatomy & Developmental Biology, Tokyo Women's Medical University School of Medicine.
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