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#28051 Anti- BACE1 (42) Rabbit IgG Affinity Purify

  • WB
  • HEK293 cells stable transtected human BECE1
  • Antigen absorptin test
Intended Use:
Research reagents
Application:
WB, ICC
Package Size1:
100 μg
Package Size2:
10 μg
Note on Application Abbreviations
WB:Western Blotting
ICC:Immunocytochemistry

※ The product indicated as "Research reagents" in the column Intended Use cannot be used
  for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
  enclosed in the product purchased before use.

Product Overview

Product Overview

Product Code 28051
Product Name Anti- BACE1 (42) Rabbit IgG Affinity Purify
Intended Use Research reagents
Application WB, ICC
Immunizing antigen Synthetic peptide of a part of human BACE1 (RLPRETDEEPEEPGRR)
Purification Method Purified with antigen peptide
Specificity Reacts with human, mouse and rat BACE1.
Package Form Lyophilized product from 1 % BSA in PBS containing 0.05 % NaN3
Storage Condition 2 - 8℃
Poisonous and Deleterious Substances Applicable
Cartagena Not Applicable
Package Size 1 100 μg
Package Size 2 10 μg
Remarks1 The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission.

Product Description

Product Description

The current understanding of the role of amyloid in Alzheimer's disease (AD) has been established by a remarkable congruence of multiple disciplines: neuropathology, biochemistry, molecular biology, and epidemiological genetics. It is known that amyloidβ is derived, by two sequential cleavages, from the receptor-like amyloid precursor protein (APP). The proteases involved are beta-secretase, identified as the novel aspartyl protease BACE, and gamma-secretase, a multimeric complex containing the presenilins (PS-1, PS-2). BACE1 and BACE2 have been isolated as homologue of BACE.

References

References