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#27707 Mouse/Rat Total Insulin CLEIA Kit - IBL

  • 27707 Mouse/Rat Total Insulin CLEIA Kit
  • 27707 Mouse/Rat Total Insulin CLEIA Kit
  • 27707 Mouse/Rat Total Insulin CLEIA Kit
  • 27707 Mouse/Rat Total Insulin CLEIA Kit
  • 27707 Mouse/Rat Total Insulin CLEIA Kit
  • 27707 Mouse/Rat Total Insulin CLEIA Kit
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Intended Use:
Research reagents
Measuring Method:
CLEIA
Sample Types:
Mouse, Rat
Measuring Samples:
EDTA-plasma, Serum
Measurement Range:
41.15 ~ 30,000 pg/mL (7 ~ 5,025 pmol/L)
Package Size1:
96 Well

Product Overview

Product Code 27707
Product Name Mouse/Rat Total Insulin CLEIA Kit - IBL
Maker Name Immuno-Biological Laboratories Co., Ltd.
Intended Use Research reagents
Measuring Method CLEIA
Conjugate ALP
Species Mouse, Rat
Measuring Samples EDTA-plasma, Serum
Measurement Range 41.15 ~ 30,000 pg/mL (7 ~ 5,025 pmol/L)
Primary Reaction Overnight at 2 ~ 8°C
Secondary Reaction 120 minutes at room temperature
Storage Condition 2~8°C
Poisonous and Deleterious Substances Not Applicable
Cartagena Not Applicable
Measuring Service Not Available
Package Size 1 96 Well

Product Description

Insulin is peptide hormone that is released from the beta cells of the islets of Langerhans of pancreas. 
It is synthesized as 86 amino-acid precursor “proinsulin” and it is cleaved by C-peptide and insulin that consists of 21 amino-acid A-chain and 30 amino-acid β chain that is linked by disulfide binding due to activation of prohormone conversion enzyme (PC2, PC3) in secretory granule.
Insulin deposits glucose and promotes synthesize protein in skeletal muscles. It also has physiological function such as suppress gluconeogenesis in liver and it has been known as an only hormone that can decrease blood glucose.    
Insulin is constantly released to maintaining the level of blood glucose while it is also released in large amount stimulated by incretin and glucose for suppressing rapidly increased blood glucose after meal.
However, lack of insulin secretion and decreasing insulin sensitivity are observed and eventually high blood glucose is observed in diabetic conditions.
Measuring insulin in fasting (F-IRI) is required for clinical assessment of diabetes such as function of insulin secretion and insulin resistance.
This CLEIA kit has a wide measurement range to measure the total insulin
(insulin and proinsulin) at low level in fasting and at high level after loading
using only 5 μL sample.



Keywords:
GIP / GLP-1 / Insulin / Incretin

Note: This product is for research use only. It cannot be used as a diagnostic tool or drug.