Product News
- Product News2026/07/06
- sCLEC-2 ELISA Kit – IBL New release!
Any IBL product introduced in this IBL news is applicable for research use only and it cannot be used for diagnosis or medical purpose.We are pleased to announce that we start to sell #27820 sCLEC-2 ELISA Kit – IBL.
【Reference】
Fuminori Kazama et al. Measurement of soluble C-type lectin-like receptor 2 in human plasma. Platelets. 2015;26(8):711-9. PMID: 25856065
Osamu Inoue et al. Soluble CLEC-2 is generated independently of ADAM10 and is increased in plasma in acute coronary syndrome: comparison with soluble GPVI. Int J Hematol. 2019;110(3):285-294. PMID: 31165998
#27820 sCLEC-2 ELISA Kit – IBL
CLEC-2 (C-type lectin-like receptor 2) is identified as the receptor for the platelet-activating snake venom, rhodocytin, and is predominantly expressed in platelets and megakaryocytes. It has been implicated in various physiological and pathological processes, including cancer metastasis and thrombosis.
Platelets are activated by factors such as collagen and shear stress when the vascular wall is damaged by trauma or inflammation. During this process, membrane-bound CLEC-2 is cleaved by platelet-derived proteases and shed into the bloodstream as soluble CLEC-2 (sCLEC-2). Furthermore, CLEC-2 is also considered to be released in association with platelet-derived microparticles generated during platelet activation, suggesting that sCLEC-2 is present in the circulation in multiple forms, including microparticle-associated forms.
It has been reported that blood levels of sCLEC-2 are increased in arterial thrombosis, such as cerebral infarction and myocardial infarction, and further studies are warranted. Citrated plasma is recommended for measurement.
#27820 sCLEC-2 ELISA Kit – IBL is available to detect both shed and microparticle-associated CLEC‑2
We hope that we can support your research.
Please feel free to contact us.
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Antibody related Business Division
Immuno-Biological Laboratories Co., Ltd.
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