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#28023 Anti- Drebrin A (DAS2) Rabbit IgG Affinity Purify (Discontinued : Current stock only)

  • WB
  • cultured hippocampal neuron (16 DIV, scale bar, 10 mm)
  • adult rat cerebral cortex (10 mm section, scale bar, 10 mm)
Intended Use:
Research reagents
Application:
WB, IHC, ICC
Package Size1:
50 μg
Package Size2:
5 μg
Note on Application Abbreviations
WB:Western Blotting
IHC:Immunohistochemistry
ICC:Immunocytochemistry

※ The product indicated as "Research reagents" in the column Intended Use cannot be used
  for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
  enclosed in the product purchased before use.

Product Overview

Product Overview

Product Code 28023
Product Name Anti- Drebrin A (DAS2) Rabbit IgG Affinity Purify (Discontinued : Current stock only)
Intended Use Research reagents
Application WB, IHC, ICC
Immunizing antigen Synthetic peptide of the part of Drebrin A (FIKASDSGPSSS)
Purification Method Purified with antigen peptide
Specificity Reacts with rat and mouse Drebrin A.
Package Form Lyophilized product from PBS containing 1 % BSA and 0.05 % NaN3
Storage Condition 2 - 8℃
Poisonous and Deleterious Substances Applicable
Cartagena Not Applicable
Package Size 1 50 μg
Package Size 2 5 μg
Remarks1 The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission.

Product Description

Product Description

Drebrin (developmentally regulated brain protein), isolated and identified from chicken brain as a protein associated with brain development, is conserved over species, and there are two types of isoforms, drebrin A and drebrin E in mammalian such as rat and human. Drebrin has actin filament-binding activity and has drawn attention as a protein generally involved in biological phenomena related to intracellular actin cytoskeletal system including cell migration. Drebrin A is present specifically at neuron dendritic spines in adult brain and is considered to be related in its morphogenesis, synaptic transmitter function and plasticity. Drebrin A is reported to ecrease in Alzheimer's disease, Down syndrome and aged brain, and it is suggested that drebrin A is related to decline of cognitive function. This antibody specifically reacts with drebrin A among isoforms of drebrin.