keyword |
title |
author |
published |
spiecies |
specimen |
item |
Gut microbiome, Mucosal barrier, Inflammation, Local immune responses |
Aberrant Gut Microbiome Contributes to Barrier Dysfunction, Inflammation, and Local Immune Responses in IgA Nephropathy. |
Tang Y et al. |
01Mar 6, 2023 |
Human |
Plasma, urine |
Antibody |
Oral cavity, Cnm-positive Streptococcus mutans |
cnm-positive Streptococcus mutans is associated with galactose-deficient IgA in patients with IgA nephropathy. |
Misaki T et al. |
02Mar 2, 2023 |
Human |
Plasma |
ELISA, Antibody |
Disease Activity, Progression |
Serum levels of galactose-deficient IgA are elevated in patients with IgA nephropathy but do not correlate to disease activity or progression. |
Sigridur Eliasdottir et al. |
03Jan 25, 2023 |
Human |
Serum, urine |
ELISA |
O-glycan, N-acetylgalactosamine, IgA1 hinge region |
Racial heterogeneity of IgA1 hinge-region O-glycoforms in patients with IgA nephropathy. |
Ohyama Y et al. |
04Sep 27, 2022 |
Human |
Serum |
ELISA |
Zonulin |
Zonulin, as a marker of intestinal permeability, is elevated in IgA nephropathy and IgA vasculitis with nephritis. |
Li Q et al. |
05Sep 20, 2022 |
Human |
EDTA plasma |
ELISA |
Factor Ba/C5a, Oxford Pathology Classification of IgA Nephropathy |
Associations between Biomarkers of Complement Activation, Galactose-Deficient IgA1 Antibody and the Updated Oxford Pathology Classification of IgA Nephropathy. |
Juan YT et al. |
06Jul 21, 2022 |
Human |
Plasma |
ELISA |
Urinary Gd-IgA1 |
Galactose-Deficient IgA1 as a Candidate Urinary Marker of IgA Nephropathy. |
Fukao Y et al. |
07Jun 2, 2022 |
Human |
Serum, urine |
Antibody |
APRIL, VIS649 |
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of VIS649 (Sibeprenlimab), an APRIL-Neutralizing IgG2 Monoclonal Antibody, in Healthy Volunteers |
Mathur M et al. |
08Feb 8, 2022 |
Human |
Serum |
ELISA |
Sialylated IgG |
Sialylation of IgG inhibits the formation of galactose-deficient IgA1-containing immune complexes and protects mesangial cells from injury in IgA nephropathy. |
Liu Y et al. |
09Jan 11, 2022 |
Human |
Cell supernatants of PBMCs |
ELISA |
TNFR1, IgAVN, Children |
Relationship between Gd-IgA1 and TNFR1 in IgA nephropathy and IgA vasculitis nephritis in children – multicenter study. |
Mizerska-Wasiak M et al. |
10Aug 7, 2021 |
Human |
Serum |
ELISA |
APRIL |
Measurement of galactosyl-deficient IgA1 by the monoclonal antibody KM55 contributes to predicting patients with IgA nephropathy with high risk of long-term progression. |
Martín-Penagos L et al. |
11Jul 28, 2021 |
Human |
Serum |
ELISA |
Complement C5a, Factor Ba |
Alternative Complement Pathway Is Activated and Associated with Galactose-Deficient IgA1 Antibody in IgA Nephropathy Patients. |
Chiu YL et al. |
12Jun 10, 2021 |
Human |
Plasma |
ELISA |
Recurrent glomerulonephritis, kidney transplantation |
Clinical significance of serum galactose-deficient immunoglobulin A1 for detection of recurrent immunoglobulin A nephropathy in kidney transplant recipients. Kidney Res Clin Pract. |
Park WY et al. |
13Apr 15, 2021 |
Human |
Serum |
ELISA |
Membranous-like glomerulonephritis, Primary Sjögren’s syndrome |
Glomerulonephritis with severe nephrotic syndrome induced by immune complexes composed of galactose-deficient IgA1 in primary Sjögren's syndrome: a case report. |
Nishioka R et al. |
14Mar 25, 2021 |
Human |
IHC |
Antibody |
Alport syndrome |
Utility of glomerular Gd-IgA1 staining for indistinguishable cases of IgA nephropathy or Alport syndrome. |
Ishiko S et al. |
15Mar 20, 2021 |
Human |
IHC |
Antibody |
IgA-dominant infection-related glomerulonephritis |
KM55 Monoclonal Antibody Staining in IgA-Dominant Infection-Related Glomerulonephritis. |
Zhang M et al. |
16Feb 17, 2021 |
Human |
IHC |
Antibody |
Clinical Relevance |
Clinical Relevance of Serum Galactose Deficient IgA1 in Patients with IgA Nephropathy. |
Kim JS et al. |
17Nov 4, 2020 |
Human |
Serum |
ELISA |
Tonsillectomy (TE), Mesangial Gd-IgA1 immunoreactivity |
Association Between Galactose-Deficient IgA1 Derived From the Tonsils and Recurrence of IgA Nephropathy in Patients Who Underwent Kidney Transplantation. |
Kawabe M et al. |
18Sep 3, 2020 |
Human |
Serum, IF |
ELISA, Antibody |
Pediatric, Glomerular Diseases |
Glomerular galactose-deficient IgA1 expression analysis in pediatric patients with glomerular diseases. |
Ishiko S et al. |
19Aug 20, 2020 |
Human |
IF |
Antibody |
TLR7 |
TLR7 in B cells promotes renal inflammation and Gd-IgA1 synthesis in IgA nephropathy. |
Zheng N et al. |
20Jul 23, 2020 |
Human |
Supernatant collected from EBV-immortalized B cells |
ELISA |
ST6Gal1, C1GalT1 |
ST6Gal1 is up-regulated and associated with aberrant IgA1 glycosylation in IgA nephropathy: An integrated analysis of the transcriptome. |
Liu Y et al. |
21Jul 17, 2020 |
Human |
Plasma, cell culture supernatant |
ELISA |
Helicobacter pylori |
Helicobacter pylori infection is associated with elevated galactose-deficient IgA1 in IgA nephropathy. |
Liu XZ et al. |
22Jun 11, 2020 |
Human |
Plasma |
ELISA |
Children |
Clinical Significance of Serum Galactose-Deficient IgA1 Level in Children with IgA Nephropathy. |
Irabu H et al. |
23May 21, 2020 |
Human |
Serum |
ELISA |
Henoch-Schönlein purpura nephritis |
A cross-sectional analysis of clinicopathologic similarities and differences between Henoch-Schönlein purpura nephritis and IgA nephropathy. |
Sugiyama M et al. |
24Apr 23, 2020 |
Human |
Serum, IHC |
ELISA, Antibody |
C1GALT1 |
C1GALT1 expression is associated with galactosylation of IgA1 in peripheral B lymphocyte in immunoglobulin a nephropathy. |
Xing Y et al. |
25Jan 15, 2020 |
Human |
Plasma |
ELISA |
Secondary IgA Nephropathy |
Secondary IgA Nephropathy Shares the Same Immune Features With Primary IgA Nephropathy. |
Wang M et al. |
26Nov 6, 2019 |
Human |
IF |
Antibody |
Uric acid, Total IgA levels, Complement activation products |
Clinical Significance of Galactose-Deficient IgA1 by KM55 in Patients with IgA Nephropathy. |
Zhang K et al. |
27Oct 1, 2019 |
Human |
Plasma, IHC |
ELISA, Antibody |
APRIL, IL-6, TLR9 |
TLR9 activation induces aberrant IgA glycosylation via APRIL- and IL-6-mediated pathways in IgA nephropathy. |
Makita Y et al. |
28Sep 5, 2019 |
ddy mouse |
Serum |
Antibody |
Biomarker, Serum galactose deficient IgA1 |
Significance of serum galactose deficient IgA1 as a potential biomarker for IgA nephropathy: A case control study. |
Bagchi S et al. |
29May 27, 2019 |
Human |
Serum |
ELISA |
IgA vasculitis, systemic form, skin-limited form, Henoch-Schönlein purpura |
Galactose-deficient IgA1 in skin and serum from patients with skin-limited and systemic IgA vasculitis. |
Neufeld M et al. |
30Mar 19, 2019 |
Human |
IHC |
Antibody |
PST(GalNAc)PP |
Galactose-Deficient IgA1-Specific Antibody Recognizes GalNAc-Modified Unique Epitope on Hinge Region of IgA1. |
Yamasaki K et al. |
31Dec 28, 2018 |
- |
synthetic peptide |
Antibody |
Henoch-Schönlein purpura nephritis (HSPN), lupus nephritis (LN), ANCA-associated vasculitis (AAV), minimal change disease (MCD) |
Clinical significance of serum and mesangial galactose-deficient IgA1 in patients with IgA nephropathy. |
Wada Y et al. |
32Nov 2, 2018 |
Human |
Serum, IHC |
ELISA, Antibody |
IgA nephropathy, Galactose-deficient IgA1, Immune complexes, Biomarker |
Biomarkers for IgA nephropathy on the basis of multi-hit pathogenesis. |
Suzuki H. |
33Jan 9, 2018 |
Human |
Serum |
Antibody |
IgA vasculitis, renal biopsy |
IgA nephropathy and IgA vasculitis with nephritis have a shared feature involving galactose-deficient IgA1-oriented pathogenesis. |
Suzuki H et al. |
34Jan 9, 2018 |
Human |
IF |
Antibody |
ELISA, galactose-deficient IgA1, IgA nephropathy |
Novel lectin-independent approach to detect galactose-deficient IgA1 in IgA nephropathy. |
Yasutake J et al. |
35Jun 23, 2015 |
Human |
Serum, IF |
Antibody |