IBL News

We have released #27191 Human ApoA5 Assay Kit - IBL.

ApoA5 is a protein with 39kDa molecular weight that was discovered by Pennacchio et al. in 2001. It has been reported that ApoA5 is produced in liver and bounds to HDL particles and TG (Triglyceride) rich lipoprotein (CM, VLDL) and exists in blood. 

In previous studies, it has been observed that TG level in serum of ApoA5 knockout mice is significantly elevated while it is significantly decreased in serum of the knock-in mice. In addition, since it has been also suggested that ApoA5 deficiency that is caused by ApoA5 gene mutation in human shows severe hypertriglyceridaemia, it has been noted as one of factors of regulating TG metabolism.

This ELISA can specifically measure ApoA5 in human blood.

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