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Kidney Diseases CKD, AKI, IgA Nephropathy (IgAN), Hypertension, etc.
α(Alpha)-Klotho has an important role for regulating mineral metabolism as the co-receptor of FGF23 that is extensively researched in kidney disease. IBL has an ELISA that specifically detects human soluble α-Klotho which has been IBL’s bestselling product since it was released in 2010. IBL also has a lot of unique ELISA products in the field of kidney research such as Gd-IgA1 for IgA Nephropathy, Angiotensinogen for Renin-Angiotensin-Aldosterone System (RAAS) involved in the regulation of blood pressure, as well as Soluble (Pro) Renin Receptor and AIM (Apoptosis Inhibitor of Macrophage) ELISAs.
Made in Japan Quality
IBL has maintained ISO13485 certification since 2009. All our antibodies and ELISA products are manufactured and controlled in-house at our head office and main laboratory located in Japan. We are proud and confident in the quality of our products and services.
IBL carefully conducts all processes of antibody development with the utmost attention to the process of selecting sequence, immunization, screening, and cloning to find the best antibodies for a particular purpose. Our mission is to consistently supply quality products that are both highly specific and sensitive.
IBL Products (ELISA)
α(Alpha)-Klotho is widely measured in CKD research. It is a one-transmembrane protein (130 kDa) that is expressed in kidneys and the parathyroid glands and it has an important role for regulating mineral metabolism. #27998 Human soluble α-Klotho specifically detects human solubleα-Klotho, KL1 and KL1+KL2.
Gd-IgA1 (Galactose-deficient IgA1)
Galactose-deficient IgA1 (Gd-IgA1)attracts a lot of attention as a critical effector molecule in the pathogenesis and progression of IgA Nephropathy (IgAN) in recent research.The IBL ELISA kit, using a monoclonal antibody (KM55) that specifically recognizes the galactose-deficient hinge sequence of human Gd-IgA1, is a lectin non-dependent measuring system that can quantitatively measure Gd-IgA1 in human serum. It is also suitable for large scale studies because of its stability. #27600 Human Gd-IgA1 ELISA specifically detects human Gd-IgA1 and #10777 Gd-IgA1 (KM55) MoAb can be used for IHC.
Angiotensinogen (AGT), Total / Intact (Full-Length)
Angiotensinogen (AGT) is a useful biomarker for research in hypertension as it is involved in the Renin-Angiotensin-Aldosterone System (RAAS). #27412 Human Total AGT detects both human Intact (Full-Length) and Des AI AGT that is cleaved by renin. #27742 Human Intact AGT specifically detects only human Intact AGT.