IBL News

Summer time in Japan is getting very tougher with higher temperature and humidity year by year.  Mineral balance is very important for surviving in such tough climate, so we pick up “α-Klotho” which regulates mineral metabolism as the highlight of this newsletter.

α-Klotho is a transmembrane protein, confirmed its expression in the kidneys and the parathyroid glands. In recent years, it has become clear that α-Klotho is an important molecule within a living organism regulating the metabolism of mineral such as calcium and phosphorus.

soluble α-Klotho ELISA
#27998 Human soluble α-Klotho
#27601 Mouse soluble α-Klotho



New Release!
Secreted α-Klotho
#27901 Human secreted α-Klotho 

The long N-terminal extracellular domain, which occupies most of the sequence of the α-Klotho protein, has been reported to be shedding and released in the blood, while secretory isoform with only first repeat by gene splicing (secreted α-Klotho) has been reported. 

This kit specifically measures human secreted isoforms (secreted α-Klotho) in human serum, EDTA-plasma and cerebrospinal fluid (CSF) and does not react with soluble α-Klotho derived from transmembrane α-Klotho.

Secreted α-Klotho protein function is still unclear. we hope the kit will contribute further research of secreted α-Klotho.



Please feel free to contact us.

Sales Department
Antibody related Business Division
Immuno-Biological Laboratories Co., Ltd.
Email: do-ibl@ibl-japan.co.jp

IBL-Japan (Specific Antibody Development) 2min video
IBL-Japan (Specific Antibody Development) 30sec video
LipoSEARCH® - Lipoprotein Analyzing Systems (Patented GP-HPLC Systems) 30sec video