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Product News2016/11/09
Product for Alzheimer’s disease Research / New! Amyloid β Toxic Oligomer ELISA kit
We have been working on the research and development of Alzheimer’s disease research reagents. We have a comprehensive product lineup of Amyloid Beta and APP related research reagents that we supply to drug companies, diagnostic product makers, and academic researchers around the world.

We have released a new product #27709 Human Amyloidβ Toxic Oligomer Assay Kit - IBL in late November 2016. Oligomerization ofAmyloid Beta 42 is considered as an early event in Alzheimer's diseases. Irie et al. have proposed the toxic conformer with a turn at positions 22 and 23 in Aβ42 aggregates. This toxic Amyloid Beta conformer could form stable and neurotoxic oligomers. Antibody 24B3, highly specific for Amyloid Beta Toxic Oligomer, has been developed to be applied for ELISA assay kit. This kit can detect selectively putative Amyloid Beta oligomers in CSF. 

References
Monoclonal antibody with conformational specificity for a toxic conformer of amyloid β42 and its application toward the Alzheimer's disease diagnosis. Murakami K et al. Sci Rep. 2016 Jul 4;6:29038 PMID: 27374357

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