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#10101 Anti-Human Lag (Langerhans Cells), (4D12) Mouse IgG MoAb

Intended Use：
Research reagents
Application：
IHC
Package Size1：
200 μg
Note on Application Abbreviations
IHC:Immunohistochemistry

※ The product indicated as "Research reagents" in the column Intended Use cannot be used
　 for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
　 enclosed in the product purchased before use.

Product Overview

Product Overview

Product Code 10101
Product Name Anti-Human Lag (Langerhans Cells), (4D12) Mouse IgG MoAb
Intended Use Research reagents
Application IHC
Species Human
Immunizing antigen Human Langerhans cells
Source Mouse-Mouse hybridoma　(X63 - Ag 8.653 × BALB/c mouse spleen cells)
Clone Name 4D12
Subclass IgG1
Purification Method Affinity purified with Protein A
Specificity Reacts with membrane protein of Birbeck granules
Package Form Lyophilized product in PBS containing 1 % BSA and 0.05 % NaN3
Storage Condition 2 - 8℃
Poisonous and Deleterious Substances Applicable
Cartagena Not Applicable
Package Size 1 200 μg
Remarks1 The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission.

Product Description

Product Description

Langerhans cells (LC) were reported to function as the antigen-presenting cells in the skin. They express immune response gene-associated antigens on their cell membranes. These cells seem to mediate contact sensitivity in vivo and the antigen-specific response of T lymphocytes in vitro. Langerhans cells also have surface receptors for the Fc portion of immunoglobulin G (IgG) and for the third component of complement, C3. They originate from the bone marrow, but details about the precursors of LC are not known. This antibody reacts specifically to human LC. The protein recognized by this antibody was mainly in the membranes of Birbeck granules and related structures.
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