IBL News

S. Yamashita et al, Department of Cardiology, Rinku General Medical Center, Osaka, Japan has reported their research results which is a comparison between GP-HPLC (LipoSEARCH®) and NMR method by lipoprotein particle numbers of 212 dyslipidemia patients who were given pemafibrate (selective PPARα Modulator) in phase II clinical study. 

In the result, they have concluded that it has been observed certain level of correlation between the two methods in major classes, such as total Chylomicron (CM), LVDL, total LDL and total HDL, while lipoprotein particle number analyzed by GP-HPLC (LipoSEARCH®) is more accurately than NMR.

Highlights of the Publication

For more details, please refer to the following original publication.
Yamashita S et al. Distinct Differences in Lipoprotein Particle Number Evaluation between GP-HPLC and NMR: Analysis in Dyslipidemic Patients Administered a Selective PPARα Modulator, Pemafibrate. J Atheroscler Thromb. 2021 Feb 2. 

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