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#18635 Anti-Human Prion Protein (N) Rabbit IgG Affinity Purify

  • WB
Intended Use:
Research reagents
Application:
WB, IHC
Package Size1:
50 μg
Package Size2:
5 μg
Note on Application Abbreviations
WB:Western Blotting
IHC:Immunohistochemistry

※ The product indicated as "Research reagents" in the column Intended Use cannot be used
  for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
  enclosed in the product purchased before use.

Product Overview

Product Overview

Product Code 18635
Product Name Anti-Human Prion Protein (N) Rabbit IgG Affinity Purify
Intended Use Research reagents
Application WB, IHC
Species Human
Immunizing antigen Synthetic peptide of the N terminal part of Human Prion Protein
Purification Method Purified with antigen peptide
Specificity Confirmed by western blotting
(test by courtesy of Dr. Tetsuyuki Kitamoto, department of neuropathology, neurological institute, faculty of medicine, Kyusyu University, Fukuoka, Japan ).
Antigen peptide is 100% identical to Mouse, Rat, Gorilla and Chimpanzee.
However, cross-reactivities to those species are not tested.
Package Form Lyophilized product from 1 % BSA in PBS containing 0.05 % NaN3
Storage Condition 2 - 8℃
Poisonous and Deleterious Substances Applicable
Cartagena Not Applicable
Package Size 1 50 μg
Package Size 2 5 μg
Remarks1 The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission.

Product Description

Product Description

The prion protein (Prp) is a protein of unknown function that is expressed in both normal cells and in cells affected by Transmissible spongioform encephalopathies (TSEs) which are lethal neurodegenerative diseases affecting numerous mammals. TSEs are characterized by the conversion of the cellular protein PrPC to the disease-associated variant, PrPSC. The PrPC and PrPSC proteins share the same primary sequence and have no known posttranslational differences, and are believed to differ in folding conformation. PrpSC is found in high quantity in the brains of animals affected by TSEs, including scrapie in sheep, BSE in cattle and Creutzfeld-Jacob disease in humans.

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