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#28103 Anti-Human Gastrin Receptor (OK-524) Rabbit IgG Affinity Purify

Intended Use：
Research reagents
Application：
WB, IHC
Package Size1：
100 μg
Package Size2：
10 μg
Note on Application Abbreviations
WB:Western Blotting
IHC:Immunohistochemistry

※ The product indicated as "Research reagents" in the column Intended Use cannot be used
　 for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
　 enclosed in the product purchased before use.

Product Overview

Product Overview

Product Code 28103
Product Name Anti-Human Gastrin Receptor (OK-524) Rabbit IgG Affinity Purify
Intended Use Research reagents
Application WB, IHC
Species Human
Immunizing antigen Synthetic peptide of the C terminal part of Human Gastrin Receptor(CTPSIASLSRLSYTTIS)
Purification Method Purified with antigen peptide
Package Form Lyophilized product from 1 % BSA in PBS containing 0.05 % NaN3
Storage Condition 2 - 8℃
Poisonous and Deleterious Substances Applicable
Cartagena Not Applicable
Package Size 1 100 μg
Package Size 2 10 μg
Remarks1 The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission.

Product Description

Product Description

Gastrin is one of the most important gut-related hormones contributing to gastric acid secretion. Gastrin and the gastrin receptor (GR) are coexpressed in many gastrointestinal cancer cell lines, and gastrin is regarded as an autocrine growth factor for these cells. Thus, gastrin is important in the investigation of gastrointestinal carcinogenesis and anticancer therapy. The GR (identical with the cholecystokinin B receptor; CCKBR ) gene was cloned by Lee et al. and has an open reading frame encoding 447 amino acids with 7 transmembrane domains. To date, many studies have revealed the localization of GR in the human stomach. It has been of public interest to investigate the expression and potential role of gastrin and GR in gastric carcinogenesis and their relation to Helicobacter pylori infection and inflammation.
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