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#28103 Anti-Human Gastrin Receptor (OK-524) Rabbit IgG Affinity Purify
- Intended Use:
- Research reagents
- Application:
- WB, IHC
- Package Size1:
- 100 μg
- Package Size2:
- 10 μg
- Note on Application Abbreviations
- WB:Western Blotting
- IHC:Immunohistochemistry
※ The product indicated as "Research reagents" in the column Intended Use cannot be used
for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
enclosed in the product purchased before use.
Product Overview
Product Overview
Product Code | 28103 |
---|---|
Product Name | Anti-Human Gastrin Receptor (OK-524) Rabbit IgG Affinity Purify |
Intended Use | Research reagents |
Application | WB, IHC |
Species | Human |
Immunizing antigen | Synthetic peptide of the C terminal part of Human Gastrin Receptor(CTPSIASLSRLSYTTIS) |
Purification Method | Purified with antigen peptide |
Package Form | Lyophilized product from 1 % BSA in PBS containing 0.05 % NaN3 |
Storage Condition | 2 - 8℃ |
Poisonous and Deleterious Substances | Applicable |
Cartagena | Not Applicable |
Package Size 1 | 100 μg |
Package Size 2 | 10 μg |
Remarks1 | The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission. |
Product Description
Product Description
Gastrin is one of the most important gut-related hormones contributing to gastric acid secretion. Gastrin and the gastrin receptor (GR) are coexpressed in many gastrointestinal cancer cell lines, and gastrin is regarded as an autocrine growth factor for these cells. Thus, gastrin is important in the investigation of gastrointestinal carcinogenesis and anticancer therapy. The GR (identical with the cholecystokinin B receptor; CCKBR ) gene was cloned by Lee et al. and has an open reading frame encoding 447 amino acids with 7 transmembrane domains. To date, many studies have revealed the localization of GR in the human stomach. It has been of public interest to investigate the expression and potential role of gastrin and GR in gastric carcinogenesis and their relation to Helicobacter pylori infection and inflammation.