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#10403 Anti-Mouse c-MPL/TPOR (AMM2) Rat IgG MoAb Biotin

Intended Use:
Research reagents
Application:
WB, IP, FCM
Package Size1:
50 μg
Package Size2:
5 μg
Note on Application Abbreviations
WB:Western Blotting
IP:Immunoprecipitation
FCM:Flow Cytometry

※ The product indicated as "Research reagents" in the column Intended Use cannot be used
  for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
  enclosed in the product purchased before use.

Product Overview

Product Overview

Product Code 10403
Product Name Anti-Mouse c-MPL/TPOR (AMM2) Rat IgG MoAb Biotin
Intended Use Research reagents
Application WB, IP, FCM
Species Mouse
Immunizing antigen Recombinant protein of mouse c-MPL extracellular domain
Source Mouse-Rat hybridoma (P3X63-Ag.8.653 × Wistar rat spleen cells)
Clone Name AMM2
Subclass IgG1
Purification Method Affinity purified with Protein G
Specificity Reacts with mouse c-MPL/TPOR.
Package Form Lyophilized product in PBS containing 1 % BSA and 0.05 % NaN3
Storage Condition 2 - 8℃
Poisonous and Deleterious Substances Applicable
Cartagena Not Applicable
Package Size 1 50 μg
Package Size 2 5 μg
Remarks1 The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission.

Product Description

Product Description

Thrombopoietin promotes the growth and differentiation (proliferation) of megakaryocytes which produce platelets. TPOR (Thrombopoietin receptor), which is also called c-MPL (Myeloproliferative leukemia protein) or CD110, is a receptor for thrombopoietin. And it is suggested that TPOR may also play a role in the maintenance of hematopoietic stem cells, which are stem cells located within the bone marrow that have the potential to develop into red blood cells, white blood cells, megakaryocytes and platelets. This receptor is activated when thrombopoietin protein binds to it, and the activated receptor stimulates a signaling pathway called the JAK/STAT pathway, which transmits signals from outside the cell to the cell's nucleus and is important for controlling the production of blood cells. This antibody specifically reacts with mouse c-MPL/TPOR protein. This product is a biotinylated antibody.

FAQ

FAQ

  • Question
    Q.How do you biotinylation the antibody?
  • Answer
    A.NHS-LC-Biotin is used for the biotinylation.
  • Question
    Q.What is subclass and light chain?
  • Answer
    A.The subclass is Rat IgG1. The light chain is lambda.