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#18977 Anti- Synaptotagmin IV Rabbit IgG Affinity Purify

  • WB
  • PC 12 Cell
Intended Use：
Research reagents
Application：
WB, IP, ICC
Package Size1：
100 μg
Package Size2：
10 μg
Note on Application Abbreviations
WB:Western Blotting
IP:Immunoprecipitation
ICC:Immunocytochemistry

※ The product indicated as "Research reagents" in the column Intended Use cannot be used
　 for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
　 enclosed in the product purchased before use.

Product Overview

Product Overview

Product Code 18977
Product Name Anti- Synaptotagmin IV Rabbit IgG Affinity Purify
Intended Use Research reagents
Application WB, IP, ICC
Immunizing antigen Recombinant Synaptotagmin IV C2A domain
Purification Method Affinity purified with antigen
Specificity Cross-reacts with mouse and rat Synaptotagmin IV.
Package Form Lyophilized product from 1 % BSA in PBS containing 0.05 % NaN3
Storage Condition 2 - 8℃
Poisonous and Deleterious Substances Applicable
Cartagena Not Applicable
Package Size 1 100 μg
Package Size 2 10 μg
Remarks1 The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission.

Product Description

Product Description

Synaptotagmin family proteins consist of a single N-terminal transmembrane domain and C-terminal tandem C2 domains (C2A and C2B), which have the ability to bind Ca2+ and phospholipid, and 15 synaptotagmin isoforms have been reported in the mouse and humans to date. The best-characterized isoform, synaptotagmin I, is essential for synaptic vesicle exocytosis and endocytosis. It has been reported that i) synaptotagmin IV expression is regulated by neural activity and that it is thought to be involved in synaptic plasticity, ii) that synaptotagmin IV is present on dense-core vesicles in NGF-differentiated PC12 cells and may control their exocytosis, and iii) that synaptotagmin IV regulates glutamate release by astrocytes.
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