#28049 Anti-Human Podoplanin Rabbit IgG Affinity Purify

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Intended Use：: Research reagents

Application：: WB, IHC

Package Size1：: 100 μg

Package Size2：: 10 μg

Note on Application Abbreviations: WB:Western Blotting; IHC:Immunohistochemistry

※ The product indicated as "Research reagents" in the column Intended Use cannot be used
　 for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
　 enclosed in the product purchased before use.

Product Overview

Product Code	28049
Product Name	Anti-Human Podoplanin Rabbit IgG Affinity Purify
Intended Use	Research reagents
Application	WB, IHC
Species	Human
Immunizing antigen	Synthetic peptide of the part of Human Podoplanin
Purification Method	Purified with antigen peptide
Package Form	Lyophilized product from 1% BSA in PBS containing 0.05% NaN3
Storage Condition	2 - 8℃
Poisonous and Deleterious Substances	Applicable
Cartagena	Not Applicable
Package Size 1	100 μg
Package Size 2	10 μg
Remarks1	The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission.

Product Description

Podoplanin belongs to a type-I transmembrane protein which is a sialoglycoprotein with some O-glycosylation sites. It is known as a lymphatic endothelium-specific marker and believed to have a platelet-aggregating activity and to promote hematogenous metastasis of cancer cells. Podoplanin is thought to be expressed on the shape alteration of squamous cells and to relate to transition of cytoskeletal actin structure. Also, its activity which decreases the adhesion ability of cells and promotes their metastasis has drawn researchers’ attention. Additionally, podoplanin is reported to be expressed in human tumors such as brain tumor, oral cavity cancer, head and neck cancer, esophageal cancer, lung cancer, testicular tumor, cervical cancer and malignant mesothelioma.