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#28127 Anti-Mouse C-ERC/Mesothelin (308) Rabbit IgG Affinity Purify

  • WB
  • Sample; Wild type mouse
Intended Use：
Research reagents
Application：
WB, IHC
Package Size1：
50 μg
Package Size2：
5 μg
Note on Application Abbreviations
WB:Western Blotting
IHC:Immunohistochemistry

※ The product indicated as "Research reagents" in the column Intended Use cannot be used
　 for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
　 enclosed in the product purchased before use.

Product Overview

Product Overview

Product Code 28127
Product Name Anti-Mouse C-ERC/Mesothelin (308) Rabbit IgG Affinity Purify
Intended Use Research reagents
Application WB, IHC
Species Mouse
Immunizing antigen Synthetic peptide of a part of mouse C-ERC/Mesothelin (KEPYKVDEDLIFYQNWELEA)
Purification Method Purified with antigen peptide
Package Form Lyophilized product in PBS containing 1 % BSA and 0.05 % NaN3
Storage Condition 2 - 8℃
Poisonous and Deleterious Substances Applicable
Cartagena Not Applicable
Package Size 1 50 μg
Package Size 2 5 μg
Remarks1 The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission.

Product Description

Product Description

Erc has been identified as a gene showing stronger expression in cancer-affected renal tissue than in normal renal tissue in Eker rats (a rat model of renal cancer). The human homologue of the protein encoded by this gene is called MPF (megakaryocyte potentiating factor) or mesothelin. This protein is detected especially prominently in mesothelial cells, and its involvement has been suggested in the development of mesothelioma, making it a promising tumor marker. In humans, involvement of this protein has also been suggested in the development of pancreatic, ovarian and pulmonary cancers, etc. The protein is expressed as a GPI anchor-type membranous protein (about 71 kDa in molecular weight), which is thought to be digested by a furin-like protease to yield fragments about 31 kDa of N-terminal side and about 40 kDa of C-terminal side. We think it is helpful for research of ERC/Mesothelin protein and have characterized the 31 kDa fragment as N-ERC/Mesothelin and the 40 kDa fragment as C-ERC/Mesothelin. This antibody is recognizes mouse C-ERC/Mesothelin.
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