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- #28075 Anti-Mouse LRAT (Lecithin Retinol Acyltransferase) (168) Rabbit IgG Affinity Purify
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#28075 Anti-Mouse LRAT (Lecithin Retinol Acyltransferase) (168) Rabbit IgG Affinity Purify
- Intended Use:
- Research reagents
- Application:
- WB, IHC
- Package Size1:
- 50 μg
- Package Size2:
- 5 μg
- Note on Application Abbreviations
- WB:Western Blotting
- IHC:Immunohistochemistry
※ The product indicated as "Research reagents" in the column Intended Use cannot be used
for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
enclosed in the product purchased before use.
Product Overview
Product Overview
Product Code | 28075 |
---|---|
Product Name | Anti-Mouse LRAT (Lecithin Retinol Acyltransferase) (168) Rabbit IgG Affinity Purify |
Intended Use | Research reagents |
Application | WB, IHC |
Species | Mouse |
Immunizing antigen | Synthetic peptide of a part of Mouse LRAT (168-184) (RYGSRISPQAEKFYDT) |
Purification Method | Purified with antigen peptide |
Specificity | Cross-reacts with rat. |
Package Form | Lyophilized product from 1 % BSA in PBS containing 0.05 % NaN3 |
Storage Condition | 2 - 8℃ |
Poisonous and Deleterious Substances | Applicable |
Cartagena | Not Applicable |
Package Size 1 | 50 μg |
Package Size 2 | 5 μg |
Remarks1 | The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission. |
Product Description
Product Description
LRAT is a retinol-esterifying enzyme and it is mainly found in G0 stage of stellate cells (Ito cells) in liver. At stellate cells, LRAT is thought to take a role engulfing and pooling excess vitamin A released from hepatocytes. As normal hepatocytes are characterized by lipid droplets pooling esterified vitamin A, LRAT is expected to be a marker of stellate cells in G0 stage. LRAT is also expressed in retinal pigment epithelium, small intestine epithelium and skin keratinocyte as well as liver. The physiological significance of LRAT protein at the endothelium is not clarified, yet. This antibody reacts with stellate cells and endothelia of mouse and rat.
WB data is kindly provided by Prof. Haruki Senoo and Dr. Yoshihiro Mezaki of
Akita University Faculty of Medicine
IHC
Arrow (Red); Hepatic stellate cells
Arrow (Yellow);Endothelial cells of portal vein
( PV; Portal vein , CV; Central vein )
Bar: 20μm , 10μm (inside)
IHC data is kindly provided by Dr. Tomokazu Matsuura and Dr. Keisuke Nagatsuma of Jikei University School of Medicine