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#10078 Anti-Rat Hepatic Sinusoidal Endothelial Cells (SE-1) Mouse IgG MoAb

  • Rat Liver
Intended Use:
Research reagents
Application:
WB, IHC
Package Size1:
100 μg
Package Size2:
10 μg
Note on Application Abbreviations
WB:Western Blotting
IHC:Immunohistochemistry

※ The product indicated as "Research reagents" in the column Intended Use cannot be used
  for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
  enclosed in the product purchased before use.

Product Overview

Product Overview

Product Code 10078
Product Name Anti-Rat Hepatic Sinusoidal Endothelial Cells (SE-1) Mouse IgG MoAb
Intended Use Research reagents
Application WB, IHC
Species Rat
Immunizing antigen Rat Hepatic Sinusoidal Endothelial Cells
Source Mouse-Mouse hybridoma (X63 - Ag 8.653 × BALB/c mouse spleen cells)
Clone Name SE-1
Subclass IgG2a
Purification Method Affinity purified with Protein A
Package Form Lyophilized product from 1% BSA in PBS containing 0.05% NaN3.
Storage Condition 2 - 8℃
Poisonous and Deleterious Substances Applicable
Cartagena Not Applicable
Package Size 1 100 μg
Package Size 2 10 μg
Remarks1 The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission.

Product Description

Product Description

Among the vascular endothelial cells, hepatic sinusoidal endothelial (HSE) cells are morphologically unique because they have open fenestrations in their cytoplasm and lack basal lamina. This unique structure is assumed to facilitate the exchange and transport of various substances between blood and hepatocytes through the space of Disse. It has been suggested that the formation of this structure is regulated by hepatocyte-related soluble factors or by the extracellular matrix. The antibody was observed no cross-reactivity with other types of endothelial cells or non-endothelial cells. By immunoelectron microscopy, the antigen recognized by the antibody was localized to the membrane surface of HSE. Immunoblot analysis revealed that the antibody recognized a single 45 kDa band. The antibody may be a useful marker to study the role of HSE in various pathophysiological conditions of the liver.

FAQ

FAQ

  • Question
    Q.Can this antibody be used on human or mice samples?
  • Answer
    A.No it cannot.