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#18875 Anti-Mouse/Rat Claudin-7 (C) Rabbit IgG Affinity Purify

  • WB
  • F9 Cell (without induction)
  • F9Cell (HNF 4α induction)
Intended Use:
Research reagents
Application:
WB, IHC, ICC
Package Size1:
100 μg
Package Size2:
10 μg
Note on Application Abbreviations
WB:Western Blotting
IHC:Immunohistochemistry
ICC:Immunocytochemistry

※ The product indicated as "Research reagents" in the column Intended Use cannot be used
  for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
  enclosed in the product purchased before use.

Product Overview

Product Overview

Product Code 18875
Product Name Anti-Mouse/Rat Claudin-7 (C) Rabbit IgG Affinity Purify
Intended Use Research reagents
Application WB, IHC, ICC
Species Mouse, Rat
Immunizing antigen Synthetic peptide of the C-terminal part of Mouse and Rat Claudin-7(YRAPRSYPKSNSSKEY)
Purification Method Purified with antigen peptide
Specificity Claudin-7 specific.
Not cross-react with Claudin-1, -2, -3, -4, -5, -6, -8, -12 and -15.
(confirmed by western blotting using each transfectant)
Package Form Lyophilized product from 1 % BSA in PBS containing 0.05 % NaN3
Storage Condition 2 - 8℃
Poisonous and Deleterious Substances Applicable
Cartagena Not Applicable
Package Size 1 100 μg
Package Size 2 10 μg
Remarks1 The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission.

Product Description

Product Description

The tight junction is identified as a belt-like region in which two lipid-apposing membranes lie close together (tight junction strands). Tight junction strands of the adjacent cells form tightly connected pairs. The proteins involved in the formation of tight junctions are divided into two categories: 1) integral membrane proteins, such as occludin, claudin and junctional adhesion molecule, JAM and 2) peripheral membrane proteins (cytoplasmic plaque proteins), MAGUK (membrane-associated guanylate kinase) homologue proteins, such as ZO-1, 2, 3, cingulin, symplekin, 19B1, and AF-6. In human, the claudin superfamily consists of at least 18 members, which are involved on paracellular transport as structural and functional components of tight junction. Claudins are directly associated with ZO-1, 2 and 3 and indirectly with AF-6 and cingulin. It is known that Claudin-1, -2, -6, -7, -15 are distributed at liver or kidney and Claudin-5 is distributed at vascular endothelial cells in mouse, respectively.

References

References