#10253 Anti-Human Endothelin-B Receptor (8Z11) Mouse IgG MoAb

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Intended Use：: Research reagents

Application：: WB, IHC

Package Size1：: 100 μg

Package Size2：: 10 μg

Note on Application Abbreviations: WB:Western Blotting; IHC:Immunohistochemistry

※ The product indicated as "Research reagents" in the column Intended Use cannot be used
　 for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
　 enclosed in the product purchased before use.

Product Overview

Product Code	10253
Product Name	Anti-Human Endothelin-B Receptor (8Z11) Mouse IgG MoAb
Intended Use	Research reagents
Application	WB, IHC
Species	Human
Immunizing antigen	Recombinant Human Endothelin-B Receptor (insect sf-9 cells)
Source	Mouse-Mouse hybridoma
Clone Name	8Z11
Subclass	IgG2a
Purification Method	Affinity purified with Protein A
Specificity	Confirmed by western blotting.
Package Form	Lyophilized product from PBS containing 1 % BSA and 0.05 % NaN3
Storage Condition	2 - 8℃
Poisonous and Deleterious Substances	Applicable
Cartagena	Not Applicable
Package Size 1	100 μg
Package Size 2	10 μg
Remarks1	The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission.

Product Description

Two kinds of receptors for Endothelin have been found, namely Endothelin-A (ET-A) receptor and Endothelin-B (ET-B) receptor. ET-A receptor is ET-1 specific and expressed in lung, aorta, atrium, liver, muscle, cerebral cortex, cerebellum, kidney, adrenal, duodenum, colon and placenta at the mRNA or cDNA level, while ET-B receptor lacks isopeptide specificity and is found in liver, lung, placenta, kidney, heart and brain. Cellular localization of ET-receptors in these organs or tissues, however, has not been elucidated, although stromal cells, but not epithelial cells of the breast, express ET-1 receptor in vitro.