- HOME >
- For Researchers >
- Product Search >
- Search Result >
- #18201 Anti- Endothelin-1 Rabbit IgG Affinity Purify
Product Search
#18201 Anti- Endothelin-1 Rabbit IgG Affinity Purify
- Intended Use:
- Research reagents
- Application:
- IHC
- Package Size1:
- 50 μg
- Package Size2:
- 5 μg
- Note on Application Abbreviations
- IHC:Immunohistochemistry
※ The product indicated as "Research reagents" in the column Intended Use cannot be used
for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
enclosed in the product purchased before use.
Product Overview
Product Overview
Product Code | 18201 |
---|---|
Product Name | Anti- Endothelin-1 Rabbit IgG Affinity Purify |
Intended Use | Research reagents |
Application | IHC |
Immunizing antigen | Synthetic peptide of a part of Endothelin-1 (A common parts of Bovine, Canine, Human, Mouse, Porcine and Rat) |
Purification Method | Purified with antigen peptide Absorbed by ET-3 peptide |
Specificity | Cross reacts with mouse and rat. |
Package Form | Lyophilized product from 1 % BSA in PBS containing 0.05 % NaN3 |
Storage Condition | 2 - 8℃ |
Poisonous and Deleterious Substances | Applicable |
Cartagena | Not Applicable |
Package Size 1 | 50 μg |
Package Size 2 | 5 μg |
Remarks1 | The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission. |
Product Description
Product Description
Endothelins are 21 amino acid peptides that are produced ubiquitously by vascular endothelial cells, smooth muscle cells, and other cells in different organs. Endothelins are secreted as big-endothelins that are converted to active proteins by the endothelin-converting enzyme. These peptides possess many biological activities, such as vasoconstriction and mitogenesis, and are involved in numerous physiological and pathophysiological processes in humans. Elevated plasma levels of endothelin have been associated with heart failure, and increased immunoreactivity for endothelin is observed in transplant coronary artery disease. Endothelin-1 (ET-1) is known as the most potent vasoconstrictor substance.
References
References
- Protective effects of simultaneous splenectomy on small-for-size liver graft injury in rat liver transplantation. Yoichi T et al. Transpl Int. 2014 Jan;27(1):106-13.PMID: 24164377
- Pitavastatin improves cardiac function and survival in association with suppression of the myocardial endothelin system in a rat model of hypertensive heart failure. Saka M et al. J Cardiovasc Pharmacol. 2006 Jun;47(6):770-9.PMID: 16810078
Note: Retrieve by PMID number in displayed by abstract: http://www.ncbi.nlm.nih.gov