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#28039 Anti-Human Rictor (R1291) Rabbit IgG Affinity Purify

  • WB
Intended Use:
Research reagents
Application:
WB, IP
Package Size1:
100 μg
Package Size2:
10 μg
Note on Application Abbreviations
WB:Western Blotting
IP:Immunoprecipitation

※ The product indicated as "Research reagents" in the column Intended Use cannot be used
  for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
  enclosed in the product purchased before use.

Product Overview

Product Overview

Product Code 28039
Product Name Anti-Human Rictor (R1291) Rabbit IgG Affinity Purify
Intended Use Research reagents
Application WB, IP
Species Human
Immunizing antigen Synthetic peptide of a part of Human Rictor (GSSHTLPRRAQSLKA)
Purification Method Purified with antigen peptide
Package Form Lyophilized product from 1% BSA in PBS containing 0.05% NaN3
Storage Condition 2 - 8℃
Poisonous and Deleterious Substances Applicable
Cartagena Not Applicable
Package Size 1 100 μg
Package Size 2 10 μg
Remarks1 The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission.

Product Description

Product Description

Rictor (rapamycin-insensitive companion of mTOR/ mAVO3) is about 200 kDa and identified as an mTOR-binding protein. Rictor is a factor that constitutes a complex with mLST8 and Sin 1 which is called mTORC2 (mTOR complex 2), and it is contrasted with raptor in mTORC1. It has a domain structure which is rather conserved over species, and these are thought to be necessary for formation of mTORC2 and binding to substrates, but then the details of their functions are not clear. Regulation of actin-cytoskeletal organization through mediation of Rho family (low molecular weight GTP-binding protein) and PKCα, and phosphorylation of hydrophobic motif site at the C-terminal of PKB/Akt have been reported as effects of mTORC2 including rictor.