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#28063 Anti-Human GBF1 (1844) Rabbit IgG Affinity Purify

  • GBF1 antibody (W.B) Test Data
Intended Use：
Research reagents
Application：
WB, IP
Package Size1：
100 μg
Package Size2：
10 μg
Note on Application Abbreviations
WB:Western Blotting
IP:Immunoprecipitation

※ The product indicated as "Research reagents" in the column Intended Use cannot be used
　 for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
　 enclosed in the product purchased before use.

Product Overview

Product Overview

Product Code 28063
Product Name Anti-Human GBF1 (1844) Rabbit IgG Affinity Purify
Intended Use Research reagents
Application WB, IP
Species Human
Immunizing antigen Synthetic peptide of the C terminal part of Human GBF1(LATPRPTDPIPTSEVN)
Purification Method Purified with antigen peptide
Package Form Lyophilized product from 1% BSA in PBS containing 0.05% NaN3
Storage Condition 2 - 8℃
Poisonous and Deleterious Substances Applicable
Cartagena Not Applicable
Package Size 1 100 μg
Package Size 2 10 μg
Remarks1 The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission.

Product Description

Product Description

Recent evidences have indicated that the nutrients such as glucose and amino acids are not only bodily construction materials and energy source but also affect as signal molecules in the control of the cellular functions through the protein phosphorylation reaction. mTOR (mammalian target of rapamycin) and AMPK (AMP-activated protein kinase) which are activated by reacting to amino-acid supplementation and glucose-depletion are known as protein kinases regulated in activities by the nutrients. AMPK is regarded to be a major energy sensor in the eukaryotic cells, and it has been reported that it inhibits the mTOR pathway as well as contributing to synthesis enhancing and suppression in consumption of ATP. GBF1 (Golgi-specific brefeldin A resistance factor 1) is a novel AMPK substrate and it has been reported that the phoshorylation of GBF1 at Thr1337 plays an important role in Golgi apparatus disassembly induced under stress condition.
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