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- #28123 Anti-Human GFAT1 (S243 Phosphorylated) Rabbit IgG Affinity Purify
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#28123 Anti-Human GFAT1 (S243 Phosphorylated) Rabbit IgG Affinity Purify
- Intended Use:
- Research reagents
- Application:
- WB, IP
- Package Size1:
- 50 μg
- Package Size2:
- 5 μg
- Note on Application Abbreviations
- WB:Western Blotting
- IP:Immunoprecipitation
※ The product indicated as "Research reagents" in the column Intended Use cannot be used
for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
enclosed in the product purchased before use.
Product Overview
Product Overview
Product Code | 28123 |
---|---|
Product Name | Anti-Human GFAT1 (S243 Phosphorylated) Rabbit IgG Affinity Purify |
Intended Use | Research reagents |
Application | WB, IP |
Species | Human |
Immunizing antigen | Synthetic peptide of the phosphorylated part of human GFAT1 (CNLSRVD(pS)TTCL) |
Purification Method | Purified with antigen peptide |
Package Form | Lyophilized product from 1 % BSA in PBS containing 0.05 % NaN3 |
Storage Condition | 2 - 8℃ |
Poisonous and Deleterious Substances | Applicable |
Cartagena | Not Applicable |
Package Size 1 | 50 μg |
Package Size 2 | 5 μg |
Remarks1 | The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission. |
Product Description
Product Description
GFAT1 (Glutamine : fructose-6-phosphate amidotransferase 1) is one of nutrient-sensitive phosphoprotein which was identified as a protein phosphorylated in glucose-deprived cells.
Three nutrient signaling pathways have been widely known; (i) the mammalian target of rapamycin (mTOR) signaling pathway, (ii) AMP-activated protein kinase (AMPK) signaling pathway, and (iii) hexosamine signaling pathway.
GFAT1 was isolated, which is the first and rate-limiting enzyme for the entry of glucose into the hexosamine signaling pathway to generate UDP-GlcNAc in mammals.
Recent evidences have indicated that the signals derived from nutrients like amino acid and glucose play important roles in the control of the cellular activities as well as in synthesis of proteins and generation of ATP.
This antibody recognizes the phosphorylated part (Serine243) of human GFAT1.