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#10425 Anti-Titin-N (144A2) Mouse IgG MoAb

Intended Use:
Research reagents
Application:
ELISA
Package Size1:
100 μg
Note on Application Abbreviations
ELISA:Enzyme-Linked ImmunoSorbent Assay

※ The product indicated as "Research reagents" in the column Intended Use cannot be used
  for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
  enclosed in the product purchased before use.

Product Overview

Product Overview

Product Code 10425
Product Name Anti-Titin-N (144A2) Mouse IgG MoAb
Maker Name Immuno-Biological Laboratories Co., Ltd.
Intended Use Research reagents
Application ELISA
Species Human
Immunizing antigen Recombinant Titin (1-200)
Source Mouse-Mouse hybridoma (X63-Ag8.653×BALB/c mouse spleen cells)
Clone Name 144A2
Subclass IgG2b
Purification Method Affinity purified with ProteinA
Specificity Human Titin N-Fragment specific
Package Form Lyophilized product from in Dulbecco's-PBS
Storage Condition 2 - 8 ℃
Poisonous and Deleterious Substances Not Applicable
Cartagena Not Applicable
Package Size 1 100 μg
Remarks1 The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission.

Product Description

Product Description

Titin (connectin) is a protein that consists of 34,350 amino-acid and specifically expresses in a cross-striated muscle. The molecular weight of human titin is 3,816 kDa and it has been known that as the largest protein among of existing proteins in a living body.It is one of sarcomere structured protein that is a minimum unit of myofibrillary protein and it has a role as an elastic protein for recovering the length of shortened sarcomere by its contraction. It has been known that titin is cleaved by proteolytic enzymes such as calpain and matrix metalloprotease if muscles are damaged. Titin N-Fragment, one of these fragments, is 26kDa N-terminus fragments which is excreted into the urine. It has been researched in the field of muscular dystrophy, sports medicine, cardiac disease, NAFLD, sarcopenia and frailty and it is considered as a molecule reflects status of muscles. This antibody can be used for ELISA to detect human urinary Titin N-Fragment.