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#10038 Anti-HumanFatty Acid Synthase (FAS) (14G5) Mouse IgG MoAb

  • Human glandula sebacea
Intended Use：
Research reagents
Application：
WB, IHC
Package Size1：
100 μg
Package Size2：
10 μg
Note on Application Abbreviations
WB:Western Blotting
IHC:Immunohistochemistry

※ The product indicated as "Research reagents" in the column Intended Use cannot be used
　 for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
　 enclosed in the product purchased before use.

Product Overview

Product Overview

Product Code 10038
Product Name Anti-HumanFatty Acid Synthase (FAS) (14G5) Mouse IgG MoAb
Intended Use Research reagents
Application WB, IHC
Species Human
Immunizing antigen Synthetic peptide of human FAS
Source Mouse-Mouse hybridoma　( supernatant)
Clone Name 14G5
Subclass IgG2b
Purification Method Affinity purified with antigen peptide
Specificity FAS specific, but it sometimes shows positive signals in macrophage by immunohistochemistry.
Package Form Lyophilized product from 1 % BSA in PBS containing 0.05 % NaN3
Storage Condition 2 - 8℃
Poisonous and Deleterious Substances Applicable
Cartagena Not Applicable
Package Size 1 100 μg
Package Size 2 10 μg
Remarks1 The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission.

Product Description

Product Description

Animal fatty acid synthase (FAS) is a homodimer protein, which synthesizes long-chain fatty acids and is rich in liver, brain, breast and lung. However, the precise cellular localization of FAS in human tissue has not been elucidated. Immunohistochemistry with this antibody to human FAS revealed that in adult human tissues FAS is distributed mainly in cells with high lipid metabolism, in hormone-sensitive cells, and in a subset of epithelial cells of duodenum and stomach, colon absorptive cells, cerebral neurons, basket cells of cerebellum, deciduas, uroepithelium and epidermis. In fetal cells at 20 weeks of gestation, FAS was mainly present in proliferative epithelial cells of the digestive and respiratory systems, proximal renal tubules, adrenocortical cells, and mesenchymal and hematolymphoid cells.
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