#28149 Anti-Human Gipie Rabbit IgG Affinity Purify

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Intended Use：: Research reagents

Application：: WB, IP, IHC, ICC

Package Size1：: 100 μg

Package Size2：: 10 μg

Note on Application Abbreviations: WB:Western Blotting; IP:Immunoprecipitation; IHC:Immunohistochemistry; ICC:Immunocytochemistry

※ The product indicated as "Research reagents" in the column Intended Use cannot be used
　 for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
　 enclosed in the product purchased before use.

Product Overview

Product Code	28149
Product Name	Anti-Human Gipie Rabbit IgG Affinity Purify
Maker Name	Immuno-Biological Laboratories Co., Ltd.
Intended Use	Research reagents
Application	WB, IP, IHC, ICC
Species	Human
Immunizing antigen	Synthetic peptide of Gipie (VQEPEKRPLTPSLSQ)
Purification Method	Affinity purified with antigen peptide
Specificity	Cross-react with Human Gipie
Package Form	Lyophilized product in PBS containing 1 % BSA and 0.05 % NaN3
Storage Condition	2 - 8℃
Poisonous and Deleterious Substances	Applicable
Cartagena	Not Applicable
Package Size 1	100 μg
Package Size 2	10 μg
Remarks1	The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission.

Product Description

A new Girdin family molecule, Gipie is expressed in endothelial cells and it is induced by ER stresses. It interacts with GRP78 that is a 78kDa glucose regulatory protein. It has been reported that Gipie controls IRE1-JNK signal pathway by the interactive function and protects endothelial cells from apoptosis that is induced by ER stresses under circumstances such as atherosclerosis or vascular endothelial failure.