#10407 Anti- Poly (ADP-ribose) (10H) Mouse IgG MoAb

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Intended Use：: Research reagents

Application：: WB, IHC, ICC

Package Size1：: 100 μg

Package Size2：: 10 μg

Note on Application Abbreviations: WB:Western Blotting; IHC:Immunohistochemistry; ICC:Immunocytochemistry

※ The product indicated as "Research reagents" in the column Intended Use cannot be used
　 for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
　 enclosed in the product purchased before use.

Product Overview

Product Code	10407
Product Name	Anti- Poly (ADP-ribose) (10H) Mouse IgG MoAb
Intended Use	Research reagents
Application	WB, IHC, ICC
Immunizing antigen	Purified Poly (ADP-ribose)
Source	Mouse-Mouse hybridoma　(NS1 × BALB/c mouse spleen cells)
Clone Name	10H
Subclass	IgG3, κ
Purification Method	Affinity purified with Protein A
Package Form	Lyophilized product from PBS containing 1 % BSA and 0.05 % NaN3
Storage Condition	2 - 8℃
Poisonous and Deleterious Substances	Applicable
Cartagena	Not Applicable
Package Size 1	100 μg
Package Size 2	10 μg
Remarks1	The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission.

Product Description

The poly ADP-ribosylation is one of post translational modification of proteins, and is the addition of many ADP-ribose moieties to a protein. This protein modification is carried out by the poly ADP-ribose polymerases (PARPs), which are found in most eukaryotes, but not prokaryotes or yeast. The reaction is involved in various cellular processes and conditions, including DNA repair, transcriptional control, genomic stability, cell death and transformation, and several reports have been indicated in relation to cancer and autoimmune disease. This antibody reacts specifically to poly ADP-ribose (PAR).