Product Search

#18921 Anti-Human CDCrel-1 (C354) Rabbit IgG Affinity Purify

  • WB
  • Human cerebellum
  • Rat cerebellum
Intended Use:
Research reagents
Application:
WB, IP, IHC
Package Size1:
100 μg
Note on Application Abbreviations
WB:Western Blotting
IP:Immunoprecipitation
IHC:Immunohistochemistry

※ The product indicated as "Research reagents" in the column Intended Use cannot be used
  for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
  enclosed in the product purchased before use.

Product Overview

Product Overview

Product Code 18921
Product Name Anti-Human CDCrel-1 (C354) Rabbit IgG Affinity Purify
Intended Use Research reagents
Application WB, IP, IHC
Species Human
Immunizing antigen Synthetic peptide of part of C terminal of human CDCrel-1 (RMQEMLQRMKQQMQDQ)
Purification Method Purified with antigen peptide
Specificity Cross-reacts with Mouse and Rat
Package Form Lyophilized product from 1% BSA in PBS containing 0.05% NaN3
Storage Condition 2 - 8℃
Poisonous and Deleterious Substances Applicable
Cartagena Not Applicable
Package Size 1 100 μg
Remarks1 The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission.

Product Description

Product Description

Parkinson's Disease (PD) is a relatively common neurodegenerative disorder, which is characterized by the loss of midbrain dopamine (DA) neurons and the presence of Lewy bodies, proteinaceous cytoplasmic inclusions that are abundantly enriched in ubiquitin. It is identified a number of potential substrates for parkin, which may be involved in the pathogenesis of PD. One of parkin's potential substrates is CDCrel-1. Mutations in parkin impair its ability to regulate the turnover of CDCrel-1. CDCrel-1 belongs to a family of septin GTPases and may regulate synaptic vesicle release in the nervous system.