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#18921 Anti-Human CDCrel-1 (C354) Rabbit IgG Affinity Purify
- Intended Use:
- Research reagents
- Application:
- WB, IP, IHC
- Package Size1:
- 100 μg
- Package Size2:
- 10 μg
- Note on Application Abbreviations
- WB:Western Blotting
- IP:Immunoprecipitation
- IHC:Immunohistochemistry
※ The product indicated as "Research reagents" in the column Intended Use cannot be used
for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
enclosed in the product purchased before use.
Product Overview
Product Overview
Product Code | 18921 |
---|---|
Product Name | Anti-Human CDCrel-1 (C354) Rabbit IgG Affinity Purify |
Intended Use | Research reagents |
Application | WB, IP, IHC |
Species | Human |
Immunizing antigen | Synthetic peptide of part of C terminal of human CDCrel-1(RMQEMLQRMKQQMQDQ) |
Purification Method | Purified with antigen peptide |
Specificity | Cross-reacts with Mouse and Rat |
Package Form | Lyophilized product from 1% BSA in PBS containing 0.05% NaN3 |
Storage Condition | 2 - 8℃ |
Poisonous and Deleterious Substances | Applicable |
Cartagena | Not Applicable |
Package Size 1 | 100 μg |
Package Size 2 | 10 μg |
Remarks1 | The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission. |
Product Description
Product Description
Parkinson's Disease (PD) is a relatively common neurodegenerative disorder, which is characterized by the loss of midbrain dopamine (DA) neurons and the presence of Lewy bodies, proteinaceous cytoplasmic inclusions that are abundantly enriched in ubiquitin. It is identified a number of potential substrates for parkin, which may be involved in the pathogenesis of PD. One of parkin's potential substrates is CDCrel-1. Mutations in parkin impair its ability to regulate the turnover of CDCrel-1. CDCrel-1 belongs to a family of septin GTPases and may regulate synaptic vesicle release in the nervous system.