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#18987 Anti-Human Septin 4 (N) Rabbit IgG Affinity Purify

  • WB
Intended Use:
Research reagents
Application:
WB, IHC
Package Size1:
100 μg
Package Size2:
10 μg
Note on Application Abbreviations
WB:Western Blotting
IHC:Immunohistochemistry

※ The product indicated as "Research reagents" in the column Intended Use cannot be used
  for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
  enclosed in the product purchased before use.

Product Overview

Product Overview

Product Code 18987
Product Name Anti-Human Septin 4 (N) Rabbit IgG Affinity Purify
Intended Use Research reagents
Application WB, IHC
Species Human
Immunizing antigen Synthetic peptide of the N terminal part of Human Septin 4. (GKLDPYDSSEDDKEYVG)
Purification Method Purified with antigen peptide
Specificity Cross reacts with mouse and rat.
Package Form Lyophilized product from 1 % BSA in PBS containing 0.05 % NaN3
Storage Condition 2 - 8℃
Poisonous and Deleterious Substances Applicable
Cartagena Not Applicable
Package Size 1 100 μg
Package Size 2 10 μg
Remarks1 The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission.

Product Description

Product Description

A cytoskeletal or scaffold protein family named “septin” has been shown to be involved in diverse phenomena in the living body, including cell division. The term “septin” is derived from “septation,” which means division. The protein was discovered as a GTP-bound protein (a polymer) indispensable for the division of yeast cells. Several to dozens of septin subunits are linked together to form filaments tens of nanometers in length. Multiple such filaments combine to form structures assuming the shapes of ribbons, rings or spirals, measuring on the order of submicrons in size. In multicellular organisms, septin is known to be involved in cell division as well as in diverse cell functions after differentiation, although the exact nature of its actions remain to be determined. Among the members of the mammalian septin family, septin 4 (H5) is unique in terms of its primary structure and expression pattern. While its expression has also been demonstrated in the heart, liver and testis, it is most prominently expressed in some neurons and glial cells. It has been suggested that septin 4 may not usually be involved in cell division. Abnormal levels or locations of septin expression have been reported in humans with cancer, degenerative neurological diseases (e.g., Parkinsonism), male sterility, etc.