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#10335 Anti-Human Tenascin-C (Domain B) (4C8MS) Mouse IgG MoAb

  • WB
  • 3556_ext_08_en_0_S.jpg
Intended Use:
Research reagents
Application:
WB, IHC
Package Size1:
100 μg
Package Size2:
10 μg
Note on Application Abbreviations
WB:Western Blotting
IHC:Immunohistochemistry

Product Overview

Product Code 10335
Product Name Anti-Human Tenascin-C (Domain B) (4C8MS) Mouse IgG MoAb
Intended Use Research reagents
Application WB, IHC
Species Human
Immunizing antigen Human Recombinant Tenascin-C
Source Mouse-Mouse hybridoma (Sp2/0×BALB/c mouse, supernatant)
Clone Name 4C8MS
Subclass IgG1
Purification Method Affinity purified with Protein A
Specificity Reacts with domain B in FNIII repeatsof Tenascin-C.
Cross-reacts with mouse and rat
Package Form Lyophilized product from 1 % BSA in PBS containing 0.05 % NaN3
Storage Condition 2 - 8℃
Poisonous and Deleterious Substances Applicable
Cartagena Not Applicable
Package Size 1 100 μg
Package Size 2 10 μg
Remarks1 The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission.

Product Description

Tenascin-C (TN-C) is a component of the extracellular matrix (ECM) that has been shown to be involved in tissue interactions during fetal development and oncogenesis. It is glycoprotein consisting of six disulphide monomer isoforms being generated by alternative splicing. A high molecular weight variant that is generated by alternative splicing of RNAs of TN-C was found predominantly in breast, prostatic and colorectal cancers. The appearance of such a large TN-C isoform has been suggested to be of significance for tumour progression.

FAQ

  • Question
    Q.What can be used for positive control?
  • Answer
    A.Cancer cellline such as NB-1 can be used as the positive control.

Note: This product is for research use only. It cannot be used as a diagnostic tool or drug.