#10335 Anti-Human Tenascin-C (Domain B) (4C8MS) Mouse IgG MoAb

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Intended Use：: Research reagents

Application：: WB, IHC

Package Size1：: 100 μg

Package Size2：: 10 μg

Note on Application Abbreviations: WB:Western Blotting; IHC:Immunohistochemistry

※ The product indicated as "Research reagents" in the column Intended Use cannot be used
　 for diagnostic nor any medical purpose.
※ The datasheet listed on this page is sample only. Please refer to the datasheet
　 enclosed in the product purchased before use.

Product Overview

Product Code	10335
Product Name	Anti-Human Tenascin-C (Domain B) (4C8MS) Mouse IgG MoAb
Intended Use	Research reagents
Application	WB, IHC
Species	Human
Immunizing antigen	Human Recombinant Tenascin-C
Source	Mouse-Mouse hybridoma (Sp2/0×BALB/c mouse, supernatant)
Clone Name	4C8MS
Subclass	IgG1
Purification Method	Affinity purified with Protein A
Specificity	Reacts with domain B in FNIII repeatsof Tenascin-C. Cross-reacts with mouse and rat
Package Form	Lyophilized product from 1 % BSA in PBS containing 0.05 % NaN3
Storage Condition	2 - 8℃
Poisonous and Deleterious Substances	Applicable
Cartagena	Not Applicable
Package Size 1	100 μg
Package Size 2	10 μg
Remarks1	The commercial use of products without our permission is prohibited. Please make sure to contact us and obtain permission.

Product Description

Tenascin-C (TN-C) is a component of the extracellular matrix (ECM) that has been shown to be involved in tissue interactions during fetal development and oncogenesis. It is glycoprotein consisting of six disulphide monomer isoforms being generated by alternative splicing. A high molecular weight variant that is generated by alternative splicing of RNAs of TN-C was found predominantly in breast, prostatic and colorectal cancers. The appearance of such a large TN-C isoform has been suggested to be of significance for tumour progression.