Product Search

#27709 Human Amyloid β Toxic Oligomer Assay Kit - IBL

  • #27709 Human Amyloid β Toxic Oligomer ELISA Kit
  • #27709 Human Amyloid β Toxic Oligomer ELISA Kit
  • #27709 Human Amyloid β Toxic Oligomer ELISA Kit
  • #27709 Human Amyloid β Toxic Oligomer ELISA Kit
  • #27709 Human Amyloid β Toxic Oligomer ELISA Kit
  • #27709 Human Amyloid β Toxic Oligomer ELISA Kit
  • 4738_ext_08_en_0_S.jpg
  • 4738_ext_08_en_1_S.jpg
  • 4738_ext_08_en_2_S.jpg
  • 4738_ext_08_en_3_S.jpg
  • 4738_ext_08_en_4_S.jpg
  • 4738_ext_08_en_5_S.jpg
Intended Use:
Research reagents
Measuring Method:
ELISA
Sample Types:
Human
Measuring Samples:
CSF
Measurement Range:
3.13 ~ 200 pg/mL
Package Size1:
96 Well

Product Overview

Product Code 27709
Product Name Human Amyloid β Toxic Oligomer Assay Kit - IBL
Maker Name Immuno-Biological Laboratories Co., Ltd.
Intended Use Research reagents
Measuring Method ELISA
Conjugate HRP
Species Human
Measuring Samples CSF
Measurement Range 3.13 ~ 200 pg/mL
Primary Reaction Overnight at 2 - 8 ℃
Secondary Reaction 60 minutes at 2 - 8 ℃
Sensitivity 0.27 pg/mL
Specificity Compound Cross Reactivity
Human Aβ (1-40) ≦0.1% 
Human Aβ (1-42) ≦0.1% 
Storage Condition 2 - 8 ℃
Poisonous and Deleterious Substances Not Applicable
Cartagena Not Applicable
Measuring Service Available
Package Size 1 96 Well

Product Description

Oligomerization of Amyloidβ (Amyloid Beta) 42 is considered as an early event in Alzheimer ’s disease (AD). Irie et al. have proposed their hypothesis from the study of systematic proline scanning and solid-state NMR that Amyloid Beta conformer with a turn structure at positions 22 and 23 in aggregation of Amyloid Beta 42 is much high toxicity and it is also easily formed to become an oligomer.1) It has been considered that the toxic Amyloid Beta conformer is stable and easily formed to become a neurotoxic oligomer. The antibody (clone: 24B3) specifically detects a toxic Amyloid Beta conformer was established for development of the ELISA assay kit.2) This kit can measure selectively putative Amyloid Beta Oligomer in CSF.

The control set is available for sale on request. Learn More

Kyewords:
Alzheimer's Disease / Amyloid β / Amyloid Beta / Beta Amyloid / Aβ / Oligomers / Toxic Oligomers / ELISA / Amyloidβ (1-42) / Amyloidβ (1-40) / Diabetes

FAQ

  • Question
    Q.Is composition of EIA buffer of each ELISA kit all same? Can it be mixed to use?
  • Answer
    A.No it isn't. As constitute of each EIA buffer is different, it cannot be mixed with other lots or EIA buffers contained in other kind of ELISA kits.
  • Question
    Q.What is the composition of concentrated wash buffer?
  • Answer
    A.It contains ordinary Tween and phosphate buffer (0.05% Tween-20 in PB).
  • Question
    Q.What is the feature of the plate?
  • Answer
    A.We use plate that is flat bottom and removable strip type plate (8wellx 12 strips).
  • Question
    Q.Can I re-use standard after reconstitution?
  • Answer
    A.Not recommended to re-use standard after reconstitution. Please use it at once after the reconstitution.
  • Question
    Q.What is different between reagent blank and test sample blank?
  • Answer
    A.Reagent blank means a well is only added EIA buffer and the purpose is confirming whether the measuring value is influenced by lack of washing process. Test sample blank means a well is added EIA buffer and HRP antibody and the purpose is to calculate the background.
  • Question
    Q.How many samples can be measured by this kit?
  • Answer
    A.The pre-coated plate contained in our ELISA kit is 96 wells plate. We recommend to use 16 wells (2 slits) for standard and 80 wells (10 slits) for 40 samples in duplicate.

Note: This product is for research use only. It cannot be used as a diagnostic tool or drug.